Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC470H765N123O136S9

DescriptionStandard

        MKLFLVLIILQFEVPTDTARPRKCFSTITGYCRKKCGMGEIYEMACLNGKLCCVNEDENKKHKKAPESPHSLPQPDGKTDYVILPTTTLLTVQL
    

Molecular Weight10603.43 Da

Isoelectric Point (pI)8.55

Net Charge (pH 7.0)2.62

Net Charge (pH 7.4) 2.19

Charge Density (pH 7.0) 0.0279

GRAVY Index-0.22

Hydrophobic Moment 0.49

Boman Index-0.00

Instability Index44.12

Aliphatic Index 85.00

Aromaticity 0.0638

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4146.34

LogP -36.40

H-bond Donors 146.0

H-bond Acceptors 150.0

Rotatable Bonds 353.0

Heavy Atoms 738.0

Ring Count 15.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0393245 VERIFIED: NO

Provenance & Taxonomy

OrganismNeomonachus schauinslandi [Animal]

FamilyDefensin

Tax ID29088

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence