Peptide Database

Peptide NameL-amino-acid oxidase (LAAO; LAO; Dactylomelin-P)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Oxidoreductase

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC109H180N36O40S3

DescriptionStandard

        DGVCSNRRQCNKEVCGSSYDVAIVGA
    

Molecular Weight2731.01 Da

Isoelectric Point (pI)6.10

Net Charge (pH 7.0)-0.27

Net Charge (pH 7.4) -0.52

Charge Density (pH 7.0) -0.0103

GRAVY Index-0.25

Hydrophobic Moment 0.38

Boman Index-0.10

Instability Index51.98

Aliphatic Index 67.31

Aromaticity 0.0385

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1262.73

LogP -18.68

H-bond Donors 47.0

H-bond Acceptors 43.0

Rotatable Bonds 91.0

Heavy Atoms 188.0

Ring Count 1.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0007500 VERIFIED: YES

Provenance & Taxonomy

OrganismAplysia dactylomela [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

RECORD: Rec_0155907 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 15.4%, E 7.7%, T 50.0%, C 26.9% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic

RECORD: Rec_0273721 VERIFIED: YES

Provenance & Taxonomy

OrganismAplysia dactylomela [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStaphylococcus aureus

Activity15 μg/mL

MethodMIC

RECORD: Rec_0404459 VERIFIED: YES

Provenance & Taxonomy

OrganismAplysia dactylomela [other]

FamilyFlavin monoamine oxidase

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Oxidoreductase Toxin Non-hemolytic

TargetNo Target Organism Found