Peptide Database

Peptide NameUnnamed

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length10 amino acids

Chemical FormulaC53H75N13O16S

DescriptionStandard

        PPPVHDFNME
    

Molecular Weight1182.31 Da

Isoelectric Point (pI)4.71

Net Charge (pH 7.0)-1.95

Net Charge (pH 7.4) -2.06

Charge Density (pH 7.0) -0.1945

GRAVY Index-0.96

Hydrophobic Moment 0.19

Boman Index0.04

Instability Index59.24

Aliphatic Index 29.00

Aromaticity 0.1000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 440.02

LogP -2.97

H-bond Donors 13.0

H-bond Acceptors 16.0

Rotatable Bonds 32.0

Heavy Atoms 83.0

Ring Count 5.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0068134 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory Antihypertensive

TargetACE

PaperIdentification of in vitro angiotensin-converting enzyme and dipeptidyl peptidase IV inhibitory peptides from draft beer by virtual screening and molecular docking. Journal of the Science of Food and Agriculture 102:1085-1094 (2022). PMID: 34309842. PMID34309842 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34309842/

RECORD: Rec_0181921 VERIFIED: NO