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MYP_002032
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Basic Information
pTAT(48–60)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Delivery / Targeting ▸ Targeting ligand ▸ Targeting
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C70H131N35O16
Standard
Sequence
GRKKRRQRRRPPQ
Physicochemical Analysis
1719.01 Da
12.00
7.76
7.55
0.5968
-3.49
0.48
-1.47
225.75
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
904.56
-11.77
34.0
24.0
61.0
121.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0338204 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: Fallypride derivative
Bio-Activity Profile
Imaging
PaperShuttle-Cargo Fusion Molecules of Transport Peptides and the hD2/3 Receptor Antagonist Fallypride: A Feasible Approach To Preserve Ligand-Receptor Binding? Evidence URLhttps://doi.org/10.1021/jm5004123
RECORD: Rec_0360803 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorophore labeling
None
N-term detail: Rhodamine-labelled
Bio-Activity Profile
Cell-penetrating peptide
CHO K1; HeLa; A549 cells
Fluorescence-based uptake assay
PMID15937518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15937518/
RECORD: Rec_0374273 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Rhodamine conjugation
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID23707662 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23707662/
RECORD: Rec_0417079 VERIFIED: YES
Provenance & Taxonomy
HIV-1 [Virus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human erythrocytes
100 μM
Hemolysis
PMID33981626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33981626/
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