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MYP_002032
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Basic Information
pTAT(48–60)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Delivery / Targeting ▸ Targeting ligand ▸ Targeting
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C70H131N35O16
Standard
Sequence
GRKKRRQRRRPPQ
Physicochemical Analysis
1719.01 Da
12.00
7.76
7.55
0.5968
-3.49
0.48
-1.47
225.75
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
904.56
-11.77
34.0
24.0
61.0
121.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0159898 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 23.1%, E 0.0%, T 23.1%, C 53.8% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Drug Delivery Vehicle Cell-penetrating peptide Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0162425 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Biotinylation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID23603097 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23603097/
RECORD: Rec_0164313 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
None
Linker 6-aminohexamoic acid (Ahx)
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID25459448 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25459448/
RECORD: Rec_0177529 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Tat
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Biotinylation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID23585561 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23585561/
RECORD: Rec_0191662 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Cys-acetamidomethyl labeling
Fluorophore labeling
N-term detail: Labelled with Cys-acetamidomethyl; C-term detail: Labelled with fluorescein maleimide
Bio-Activity Profile
Cell-penetrating peptide
HeLa
Fluorescence-based uptake assay
PMID9188504 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9188504/
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