‹ ›
MYP_002032
← PREVIOUS NEXT → BACK
Basic Information
pTAT(48–60)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Delivery / Targeting ▸ Targeting ligand ▸ Targeting
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C70H131N35O16
Standard
Sequence
GRKKRRQRRRPPQ
Physicochemical Analysis
1719.01 Da
12.00
7.76
7.55
0.5968
-3.49
0.48
-1.47
225.75
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
904.56
-11.77
34.0
24.0
61.0
121.0
2.0
14.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0007741 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Cell-penetrating peptide
Bovine erythrocytes
50 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/16137634/ PMID16137634 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16137634/
RECORD: Rec_0013715 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Rhodamine-labelled
None
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
RECORD: Rec_0042866 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: N-[2-[2-oxo-2-[[4-(10,15,20-triphenyl-21H,23H-porphin-5-yl)phenyl]amino]ethoxy]acetyl]-L-Aspartic acid
Bio-Activity Profile
Anticancer Targeting
Cancer cells
PaperPhotoinduced Cytotoxicity and Biodistribution of Prostate Cancer Cell-Targeted Porphyrins. Journal of Medicinal Chemistry. 2008 Evidence URLhttps://doi.org/10.1021/jm800444c
RECORD: Rec_0049344 VERIFIED: YES
Provenance & Taxonomy
HIV-1 [Virus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
K. rhizophila
125 μM
MIC
PMID33981626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33981626/
RECORD: Rec_0056000 VERIFIED: YES
Provenance & Taxonomy
HIV-1 [Virus]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
E. helveticus
500 μM
MIC
PMID33981626 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33981626/
1 2 3 ... 6 NEXT LAST
Showing 5 records on this page · Page 1 of 6