Peptide Database

Peptide Name[Ala6, D-Trp8]galanin-(1-15)-ol

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC82H114N20O20

DescriptionStandard

        GWTLNTAWYLLGPHA
    

Molecular Weight1699.90 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0102

GRAVY Index0.09

Hydrophobic Moment 0.25

Boman Index0.41

Instability Index1.88

Aliphatic Index 91.33

Aromaticity 0.2000

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 625.97

LogP -2.87

H-bond Donors 22.0

H-bond Acceptors 21.0

Rotatable Bonds 46.0

Heavy Atoms 122.0

Ring Count 7.0

Amide Bonds 15.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0099145 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Receptor antagonist Neuropeptide activity Signaling peptide

TargetGAL3 receptor (Rat)

Activity17.9 nM

MethodKi