Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC567H906N160O156S4

DescriptionStandard

        PQLQELFPDLPMEMQLSARRQPLLSCHPDALHGTLHGSAEAFVVLPNATRVPVFLLDIDANVTGKPTITGNRLGGTVRLTRARRVPQVKKLENVLKFGLWLFGVPWANSECDPP
    

Molecular Weight12588.50 Da

Isoelectric Point (pI)8.92

Net Charge (pH 7.0)2.22

Net Charge (pH 7.4) 1.96

Charge Density (pH 7.0) 0.0194

GRAVY Index-0.09

Hydrophobic Moment 0.60

Boman Index0.06

Instability Index47.41

Aliphatic Index 97.46

Aromaticity 0.0614

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4984.27

LogP -44.60

H-bond Donors 170.0

H-bond Acceptors 165.0

Rotatable Bonds 401.0

Heavy Atoms 887.0

Ring Count 24.0

Amide Bonds 123.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0291398 VERIFIED: NO

Provenance & Taxonomy

OrganismAsarcornis scutulata [Plant]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria