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MYP_001993
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Basic Information
17B-tF
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
17 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GXKRLVQRLKDWLRKLV
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0342454 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
unspecified non-canonical residue at 2; D amino acid, X1 = 4-methylphenylalanine, possess anti-inflammatory activity
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus Newman
25 μM
MIC
PMID31319057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31319057/
RECORD: Rec_0359203 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
unspecified non-canonical residue at 2; D amino acid, X1 = biphenylalanine; 4-t-butylphenylalanine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
A. baumannii B28-16
6.25 μM
MIC
PMID31319057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31319057/
RECORD: Rec_0359841 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
unspecified non-canonical residue at 2; D amino acid, X1 = 4-methylphenylalanine, possess anti-inflammatory activity
Bio-Activity Profile
Hemolytic
Human RBCs [Hemolytic concentration
>440 μM
Hemolysis
PMID31319057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31319057/
RECORD: Rec_0361428 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
unspecified non-canonical residue at 2; D amino acid, X1 = 4-t-butylphenylalanine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus Newman
3.1 μM
MIC
PMID31319057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31319057/
RECORD: Rec_0366576 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
unspecified non-canonical residue at 2; D amino acid, X1 = X2 = 4-t-butylphenylalanine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PAO1
6.25 μM
MIC
PMID31319057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31319057/
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