Peptide Database

Peptide NamePep-H (Human, mammals, animals)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC87H128N26O20S

DescriptionStandard

        RRYGTCIYQGRLWAF
    

Molecular Weight1890.17 Da

Isoelectric Point (pI)10.05

Net Charge (pH 7.0)2.75

Net Charge (pH 7.4) 2.53

Charge Density (pH 7.0) 0.1832

GRAVY Index-0.44

Hydrophobic Moment 0.42

Boman Index-0.11

Instability Index36.94

Aliphatic Index 58.67

Aromaticity 0.2667

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 775.99

LogP -5.21

H-bond Donors 31.0

H-bond Acceptors 24.0

Rotatable Bonds 58.0

Heavy Atoms 134.0

Ring Count 5.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0308174 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetMycobacterium tuberculosis

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