MYP_001987
Pep-H (Human, mammals, animals)
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Standard
15 amino acids
C87H128N26O20S
Standard
RRYGTCIYQGRLWAF
1890.17 Da
10.05
2.75
2.53
0.1832
-0.44
0.42
-0.11
36.94
58.67
0.2667
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
775.99
-5.21
31.0
24.0
58.0
134.0
5.0
15.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0001443
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-mycobacterial
Low cytotoxicity
Non-hemolytic
human red blood cells; human monocyte-derived macrophages
Hemolysis/RBC integrity assay; cell viability assay
RECORD: Rec_0045330
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Hemolytic
Anti-mycobacterial
Mycobacterium tuberculosis H37Rv
>90 %
CFU-based antimycobacterial killing assay (10 μg/mL peptide)
RECORD: Rec_0308174
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-mycobacterial
Mycobacterium tuberculosis H37Rv
>90 %
CFU-based antimycobacterial killing assay (10 μg/mL peptide)