Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC988H1565N269O265S6

DescriptionStandard

        PKTLPVAHEPTLLLAVTEVVANSAASTYFTAGALRRNFSSDMLPRQFPLQLRTKSMEVFSPELQQRYPDQPMELRLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPELAWPPLPVLGWAQGLPVPQVKRLETLLKFGLWLFGVPRANSKCCPHLVP
    

Molecular Weight21644.03 Da

Isoelectric Point (pI)9.66

Net Charge (pH 7.0)6.30

Net Charge (pH 7.4) 5.97

Charge Density (pH 7.0) 0.0321

GRAVY Index0.01

Hydrophobic Moment 0.55

Boman Index0.10

Instability Index52.80

Aliphatic Index 98.01

Aromaticity 0.0765

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8369.47

LogP -101.70

H-bond Donors 286.0

H-bond Acceptors 281.0

Rotatable Bonds 676.0

Heavy Atoms 1528.0

Ring Count 46.0

Amide Bonds 211.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0098674 VERIFIED: NO

Provenance & Taxonomy

OrganismCisticola juncidis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria