Peptide Database

Peptide NamehLF K7

Function Ontology

Anticancer

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC118H197N33O27S3

DescriptionStandard

        KCFQWQKNMKKVKGPPVSCIKK
    

Molecular Weight2606.23 Da

Isoelectric Point (pI)10.16

Net Charge (pH 7.0)6.73

Net Charge (pH 7.4) 6.49

Charge Density (pH 7.0) 0.3061

GRAVY Index-0.93

Hydrophobic Moment 0.46

Boman Index-0.26

Instability Index28.99

Aliphatic Index 44.09

Aromaticity 0.0909

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1004.27

LogP -7.54

H-bond Donors 35.0

H-bond Acceptors 37.0

Rotatable Bonds 91.0

Heavy Atoms 181.0

Ring Count 5.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0083046 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermFluorescein

C-TermAmidation

Disulfide2-19

Bio-Activity Profile

Function

Cell-penetrating peptide variant Cellular uptake Heparan-sulfate binding

TargetHeLa cells; Jurkat cells; heparan sulfate

MethodFlow-cytometry/confocal cellular uptake assay; isothermal titration calorimetry