Peptide Database

Peptide NameTositumomab

Function Ontology

Anticancer

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length447 amino acids

Chemical FormulaC2198H3380N574O673S16

DescriptionStandard

        QAYLQQSGAELVRPGASVKMSCKASGYTFTSYNMHWVKQTPRQGLEWIGAIYPGNGDTSYNQKFKGKATLTVDKSSSTAYMQLSSLTSEDSAVYFCARVVYYSNSYWYFDVWGTGTTVTVSGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKAEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
    

Molecular Weight49126.83 Da

Isoelectric Point (pI)8.58

Net Charge (pH 7.0)6.54

Net Charge (pH 7.4) 5.54

Charge Density (pH 7.0) 0.0146

GRAVY Index-0.41

Hydrophobic Moment 0.59

Boman Index0.02

Instability Index43.91

Aliphatic Index 67.49

Aromaticity 0.1029

Extinction Coeff. Reduced 83770.00

Extinction Coeff. Oxidized 84395.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0236716 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyMonoclonal antibody

Tax ID10090

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsLipidation

Bio-Activity Profile

Function

Anticancer Immunomodulatory Diagnostic

TargetCHO

Half-Life0.8 hours (mammalian reticulocytes, in vitro)

RECORD: Rec_0348624 VERIFIED: NO