Peptide Database

Peptide NameCecropin A1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC105H176N28O27

DescriptionStandard

        RVFKASEKALPVVTGYKAIGK
    

Molecular Weight2262.69 Da

Isoelectric Point (pI)10.17

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.1789

GRAVY Index0.01

Hydrophobic Moment 0.65

Boman Index0.03

Instability Index13.71

Aliphatic Index 92.86

Aromaticity 0.0952

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 900.50

LogP -6.81

H-bond Donors 32.0

H-bond Acceptors 31.0

Rotatable Bonds 76.0

Heavy Atoms 160.0

Ring Count 3.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0321103 VERIFIED: YES

Provenance & Taxonomy

OrganismAedes aegypti [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)