Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Metabolic ▸ Lipid metabolism ▸ Cholesterol-lowering

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC82H132N20O20

DescriptionStandard

        QEPVLGPVRGPFPIIV
    

Molecular Weight1718.05 Da

Isoelectric Point (pI)6.00

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0148

GRAVY Index0.59

Hydrophobic Moment 0.37

Boman Index0.35

Instability Index70.99

Aliphatic Index 127.50

Aromaticity 0.0625

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 606.95

LogP -2.30

H-bond Donors 18.0

H-bond Acceptors 20.0

Rotatable Bonds 48.0

Heavy Atoms 122.0

Ring Count 5.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0115600 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

Tax ID9913

Structure & Mods

Configproteolytic peptide fragment [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

RECORD: Rec_0172780 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

Tax ID9913

Structure & Mods

Configproteolytic peptide fragment [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory

TargetAngiotensin-converting enzyme (ACE)

RECORD: Rec_0213286 VERIFIED: YES

Provenance & Taxonomy

OrganismBubalus bubalis [Animal]

Tax ID89462

Structure & Mods

Configproteolytic peptide fragment [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory Antioxidant Antimicrobial Antibacterial

TargetAngiotensin-converting enzyme (ACE)

MethodACE inhibition assay

PaperComparative analysis of b-Casein proteolysis by PrtP proteinase from Lactobacillus paracasei subsp. paracasei BGHN14, PrtR proteinase from Lactobacillus rhamnosus BGT10 and PrtH proteinase from Lactobacillus helveticus BGRA43; Casein hydrolysis by Bifidobacterium longum KACC91563 and antioxidant activities of peptides derived therefrom; Novel angiotensin I-converting enzyme inhibitory peptides produced in fermented milk by specific wild Lactococcus lactis strains; Fermented Milk containing ACE-inhibitory peptides reduces blood pressure in middle aged hypertensive subjects; Identification of antihypertensive peptides derived from low molecular weight casein hydrolysates generated during fermentation by Bifidobacterium longum KACC 91563 PMID23871374;22901481;26877633 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23871374/

RECORD: Rec_0217164 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

Tax ID9913

Structure & Mods

Configproteolytic peptide fragment [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive Cholesterol-lowering Hypocholesterolemic

TargetSpontaneously hypertensive rats (SHR)

RECORD: Rec_0409650 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

Familybeta-Casein-derived

Tax ID9913

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme (ACE)

Activity600 μM

MethodIC50