Peptide Database

Peptide NameTrypsin inhibitor CyPTI-III

Function Ontology

Enzyme modulation ▸ Enzyme inhibition

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC129H213N37O43S7

DescriptionStandard

        RICPRILMECKADSDCLAQCICEESGFCG
    

Molecular Weight3194.75 Da

Isoelectric Point (pI)4.51

Net Charge (pH 7.0)-2.29

Net Charge (pH 7.4) -2.59

Charge Density (pH 7.0) -0.0790

GRAVY Index0.22

Hydrophobic Moment 0.60

Boman Index0.01

Instability Index61.13

Aliphatic Index 74.14

Aromaticity 0.0345

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1289.20

LogP -13.96

H-bond Donors 50.0

H-bond Acceptors 48.0

Rotatable Bonds 107.0

Heavy Atoms 216.0

Ring Count 2.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0167723 VERIFIED: YES

Provenance & Taxonomy

OrganismCyclanthera pedata [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-20; 10-22; 16-28

Bio-Activity Profile

Function

Trypsin inhibitor Chymotrypsin inhibitor Enzyme inhibitory

Targetbovine β-trypsin; bovine α-chymotrypsin

MethodSerine-proteinase inhibition (association constant, Ka)

RECORD: Rec_0357482 VERIFIED: YES