Peptide Database

Peptide NameProtegrin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length125 amino acids

Chemical FormulaC595H949N161O193S7

DescriptionStandard

        MEDPRARLSVGRLATVATAAGTAVPWASAQAMSYREAVLPTSILEQDEDPDAPKPVSFTVKETVCPRRTQLPPEQCDFKEKGVVKQCLGTVTLDQVKDQIDISCNKVSGPSCFELLWGEENFDDV
    

Molecular Weight13670.32 Da

Isoelectric Point (pI)4.54

Net Charge (pH 7.0)-7.52

Net Charge (pH 7.4) -7.84

Charge Density (pH 7.0) -0.0601

GRAVY Index-0.32

Hydrophobic Moment 0.43

Boman Index-0.03

Instability Index41.73

Aliphatic Index 76.40

Aromaticity 0.0560

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5666.89

LogP -60.96

H-bond Donors 195.0

H-bond Acceptors 193.0

Rotatable Bonds 445.0

Heavy Atoms 956.0

Ring Count 19.0

Amide Bonds 133.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0282190 VERIFIED: YES

Provenance & Taxonomy

OrganismCamelus dromedarius [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal