Peptide Database

Peptide NameCorticotropin-like intermediary peptide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC255H394N64O89

DescriptionStandard

        PVKVYPNGVEEESAESYPAEIRRDLSLKLDYPQGEELEEVFGGENDLLNLQ
    

Molecular Weight5780.23 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-9.02

Net Charge (pH 7.4) -9.10

Charge Density (pH 7.0) -0.1768

GRAVY Index-0.78

Hydrophobic Moment 0.47

Boman Index-0.08

Instability Index72.39

Aliphatic Index 87.84

Aromaticity 0.0784

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2475.53

LogP -22.78

H-bond Donors 81.0

H-bond Acceptors 80.0

Rotatable Bonds 193.0

Heavy Atoms 408.0

Ring Count 8.0

Amide Bonds 55.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0162410 VERIFIED: YES

Provenance & Taxonomy

OrganismAcipenser transmontanus [Animal]

FamilyCorticotropin-like intermediary peptide

Tax ID7904

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: >20 hour; Yeast: >20 hour; E. coli: ?

RECORD: Rec_0215918 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0286409 VERIFIED: NO

Provenance & Taxonomy

OrganismAcipenser transmontanus [Animal]

FamilyPOMC

Tax ID7904

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone precursor Neuropeptide precursor