Peptide Database

Peptide NameRugosin-RN antimicrobial peptide

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC364H605N93O120S6

DescriptionStandard

        MFTMKKSLLSLFFLGTISLSFCEEERSADEDDEGEMTEEEKRSIRDKIKTIAIDLAKSAGTGVLKTLICKLDKSC
    

Molecular Weight8396.64 Da

Isoelectric Point (pI)4.92

Net Charge (pH 7.0)-3.51

Net Charge (pH 7.4) -3.80

Charge Density (pH 7.0) -0.0468

GRAVY Index-0.22

Hydrophobic Moment 0.74

Boman Index-0.05

Instability Index40.09

Aliphatic Index 87.20

Aromaticity 0.0533

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3479.32

LogP -33.95

H-bond Donors 126.0

H-bond Acceptors 123.0

Rotatable Bonds 301.0

Heavy Atoms 583.0

Ring Count 4.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0352124 VERIFIED: NO

Provenance & Taxonomy

OrganismRana nigrovittata [Animal]

FamilyRugosin

Tax ID127021

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0421239 VERIFIED: NO

Provenance & Taxonomy

OrganismSylvirana [Animal]

Tax ID1659747

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal