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MYP_001780
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Basic Information
Z5
Antimicrobial
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Standard
13 amino acids
C78H147N33O14
Standard
Sequence
RRIIRIHIRIIRR
Physicochemical Analysis
1771.21 Da
12.00
5.85
5.59
0.4498
-0.25
1.02
-0.56
140.65
180.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
812.60
-4.96
33.0
21.0
63.0
125.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0084607 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on De novo designed [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
S-paratyphi ATCC 14028
32 μg/mL
MIC
PaperDe novo-designed amphiphilic alpha-helical peptide Z2 exhibits broad-spectrum antimicrobial, anti-biofilm, and anti-inflammatory efficacy in acute Pseudomonas aeruginosa pneumonia.
RECORD: Rec_0137105 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on De novo designed [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
3 strains Acinetobacter baumannii SYP-B4290/B4291/B3819
16-32 μg/mL
MIC
PaperDe novo-designed amphiphilic alpha-helical peptide Z2 exhibits broad-spectrum antimicrobial, anti-biofilm, and anti-inflammatory efficacy in acute Pseudomonas aeruginosa pneumonia.
RECORD: Rec_0271290 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on De novo designed [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
4 strains Escherichia coli ATCC 9637 or SYP-B3820/B4288/B4289
16-32 μg/mL
MIC
PaperDe novo-designed amphiphilic alpha-helical peptide Z2 exhibits broad-spectrum antimicrobial, anti-biofilm, and anti-inflammatory efficacy in acute Pseudomonas aeruginosa pneumonia.
RECORD: Rec_0315153 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on De novo designed [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
Klebsiella pneumoniae CMCC46117
16 μg/mL
MIC
PaperDe novo-designed amphiphilic alpha-helical peptide Z2 exhibits broad-spectrum antimicrobial, anti-biofilm, and anti-inflammatory efficacy in acute Pseudomonas aeruginosa pneumonia.
RECORD: Rec_0378122 VERIFIED: YES
Provenance & Taxonomy
synthetic construct based on De novo designed [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-inflammatory
Pseudomonas aeruginosa ATCC 9027
32 μg/mL
MIC
PaperDe novo-designed amphiphilic alpha-helical peptide Z2 exhibits broad-spectrum antimicrobial, anti-biofilm, and anti-inflammatory efficacy in acute Pseudomonas aeruginosa pneumonia.