MYP_001779
Linear Cyclotide Panitide L7
Anticancer
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Antimicrobial
▸
Antifungal
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
not Standard
27 amino acids
-
contains X representing unresolved or non-standard residue
XAFCGETCVLGTCYTPGCSCNFGICLK
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
RECORD: Rec_0166508
VERIFIED: YES
Provenance & Taxonomy
Steinchisma laxum [Plant]
Cyclotide
Structure & Mods
linear cyclotide scaffold [Linear]
ambiguous/noncanonical residue annotation [Modified]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
X at 1 (reported unspecified residue)
Bio-Activity Profile
Cytotoxic
Anticancer
Human cervical carcinoma HeLa
7.7 μM
IC50
RECORD: Rec_0268428
VERIFIED: NO
Provenance & Taxonomy
Panicum laxum [Plant]
Cyclotide
Structure & Mods
linear cyclotide scaffold [Linear]
modified peptide with N-terminal pyroglutamate [Modified]
Pyroglutamylation
4-18, 8-20, 13-25.
N-terminal pyroglutamic acid (X=pGlu)
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0322143
VERIFIED: YES
Provenance & Taxonomy
Steinchisma laxum [Plant]
Cyclotide
Structure & Mods
linear cyclotide scaffold [Linear]
modified peptide with N-terminal pyroglutamate [Modified]
Pyroglutamylation
None
N-terminal pyroglutamic acid (X=pGlu)
Bio-Activity Profile
Cytotoxic
Anticancer
Tumor cells: HeLa
7.7 μM
IC50
Showing 3 records · Page 2 of 2