Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC468H745N135O128S9

DescriptionStandard

        MKFLLLVLAALGFLTQVIPASGGGSKCVSDTPGYCRTHCHRGETALFMCSPFRKCCISYSFLPQPDLPQLIGNHWPSRSRNTQRKNKKQQTTVMP
    

Molecular Weight10599.33 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)8.70

Net Charge (pH 7.4) 8.23

Charge Density (pH 7.0) 0.0916

GRAVY Index-0.23

Hydrophobic Moment 0.44

Boman Index-0.00

Instability Index47.86

Aliphatic Index 69.79

Aromaticity 0.0842

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4201.37

LogP -44.70

H-bond Donors 151.0

H-bond Acceptors 149.0

Rotatable Bonds 342.0

Heavy Atoms 740.0

Ring Count 20.0

Amide Bonds 103.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0294196 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence