Peptide Database

Peptide NameSLAY-screened peptide P3870

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC80H120N18O18S

DescriptionStandard

        PLQPFYVYLNRML
    

Molecular Weight1653.98 Da

Isoelectric Point (pI)9.00

Net Charge (pH 7.0)0.96

Net Charge (pH 7.4) 0.90

Charge Density (pH 7.0) 0.0736

GRAVY Index0.23

Hydrophobic Moment 0.49

Boman Index0.21

Instability Index83.22

Aliphatic Index 112.31

Aromaticity 0.2308

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 578.28

LogP -0.76

H-bond Donors 20.0

H-bond Acceptors 20.0

Rotatable Bonds 49.0

Heavy Atoms 117.0

Ring Count 5.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0243444 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/