Peptide Database

Peptide NameProgonadoliberin-3

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length59 amino acids

Chemical FormulaC302H471N83O84S3

DescriptionStandard

        QHWSYGWLPGGKRSVGELEATIKMMDTGGVVALPEETSAHVSERLRPYDVILKKWMPHK
    

Molecular Weight6704.67 Da

Isoelectric Point (pI)8.32

Net Charge (pH 7.0)1.03

Net Charge (pH 7.4) 0.66

Charge Density (pH 7.0) 0.0175

GRAVY Index-0.51

Hydrophobic Moment 0.61

Boman Index0.00

Instability Index69.37

Aliphatic Index 75.93

Aromaticity 0.0847

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2651.43

LogP -20.70

H-bond Donors 93.0

H-bond Acceptors 91.0

Rotatable Bonds 218.0

Heavy Atoms 472.0

Ring Count 15.0

Amide Bonds 59.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0106202 VERIFIED: YES

Provenance & Taxonomy

OrganismSalvelinus fontinalis [Animal]

FamilyProgonadoliberin

Tax ID8038

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0213237 VERIFIED: YES

Provenance & Taxonomy

OrganismOncorhynchus nerka [Animal]

FamilyProgonadoliberin

Tax ID8023

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0398286 VERIFIED: YES

Provenance & Taxonomy

OrganismOncorhynchus tshawytscha [Animal]

FamilyProgonadoliberin

Tax ID74940

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0414471 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmo salar [Animal]

FamilyProgonadoliberin

Tax ID8030

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour