Peptide Database

Peptide NameLactoferrampin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC90H146N22O23

DescriptionStandard

        DLIWKLLSKAQEKFGK
    

Molecular Weight1904.26 Da

Isoelectric Point (pI)9.53

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.1100

GRAVY Index-0.48

Hydrophobic Moment 0.58

Boman Index-0.06

Instability Index10.80

Aliphatic Index 103.75

Aromaticity 0.1250

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 757.61

LogP -3.41

H-bond Donors 26.0

H-bond Acceptors 25.0

Rotatable Bonds 68.0

Heavy Atoms 135.0

Ring Count 3.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0137474 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyLactoferrampin

Tax ID9913

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetCandida albicans

MethodMIC

PaperLactoferrampin, an antimicrobial peptide of bovine lactoferrin, exerts its candidacidal activity by a cluster of positively charged residues at the C-terminus in combination with a helix-facilitating N-terminal part | Van Der Kraan, MIA. et al. | DOI: 10.1515/BC.2005.017 Evidence URLhttps://www.uniprot.org/uniprotkb/P24627/entry