Peptide Database

Peptide NamePegademase

Function Ontology

Anticancer

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length363 amino acids

Chemical FormulaC1826H2843N485O553S15

DescriptionStandard

        MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPEFLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQAEGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAIDLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGYHTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIFKSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAEQCL
    

Molecular Weight40919.00 Da

Isoelectric Point (pI)5.33

Net Charge (pH 7.0)-13.52

Net Charge (pH 7.4) -14.52

Charge Density (pH 7.0) -0.0372

GRAVY Index-0.42

Hydrophobic Moment 0.66

Boman Index-0.02

Instability Index40.76

Aliphatic Index 81.10

Aromaticity 0.0882

Extinction Coeff. Reduced 45840.00

Extinction Coeff. Oxidized 46215.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0130715 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyGrowth factor

Tax ID9913

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPEGylation

Bio-Activity Profile

Function

Enzyme replacement

Half-Lifeplasma adenosine deaminase elimination half-life is 3 to >6 days

RECORD: Rec_0289808 VERIFIED: NO