MYP_001723
Wollamide B [L2Me-Leu, N5Me-Asn]
Anticancer
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
not Standard
6 amino acids
-
contains X representing unresolved or non-standard residue
WXLVXX
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0158169
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,5,6
Bio-Activity Profile
Antimicrobial
Antibacterial
Mycobacterium tuberculosis H37Rv
80 μM
MIC
RECORD: Rec_0166706
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,5,6
Bio-Activity Profile
Antimicrobial
Antibacterial
Human hepatocellular carcinoma HepG2
100 μM
IC50
RECORD: Rec_0260721
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
x(2)=METH-Leu; l=D-Leu; x(5)=METH-Asn; x(6)=D-Orn
Bio-Activity Profile
Antimicrobial
Anticancer
Cytotoxic
RECORD: Rec_0392468
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
x(2)=METH-Leu; l=D-Leu; x(5)=METH-Asn; x(6)=D-Orn
Bio-Activity Profile
Antimicrobial
Anticancer
HepG2
100 μM
IC50
RECORD: Rec_0414400
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
x(2)=METH-Leu; l=D-Leu; x(5)=METH-Asn; x(6)=D-Orn
Bio-Activity Profile
Antimicrobial
Anticancer
Hemolytic