Peptide Database

Peptide NameDefensin-5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length171 amino acids

Chemical FormulaC787H1261N221O258S9

DescriptionStandard

        MRTLTLLAAILLLAPQAQAQPLPENAEEALEQQQPQQEDQDQDVAISSAGAENSGAQYEGESYFPTYQDPALRPQGLPAMRTLALLAAILLLALQAQAQPLPENAEEALEQQQPQQEDQDVTISFSVAGSSGLQGGASVKVCRCKTGSCGFPKAKSGSCYKHGKMAKFCCR
    

Molecular Weight18235.34 Da

Isoelectric Point (pI)4.68

Net Charge (pH 7.0)-7.44

Net Charge (pH 7.4) -7.84

Charge Density (pH 7.0) -0.0435

GRAVY Index-0.36

Hydrophobic Moment 0.49

Boman Index0.01

Instability Index64.23

Aliphatic Index 77.84

Aromaticity 0.0468

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7699.26

LogP -90.85

H-bond Donors 256.0

H-bond Acceptors 261.0

Rotatable Bonds 607.0

Heavy Atoms 1275.0

Ring Count 21.0

Amide Bonds 196.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0311103 VERIFIED: NO

Provenance & Taxonomy

OrganismFukomys damarensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence