Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length162 amino acids

Chemical FormulaC773H1209N221O225S22

DescriptionStandard

        MKAFSVAVAVVVVLACMCILESTAVPFSEVRTEEVGSIDSPVGEHQQPGSESMRPPELFRFKRQSHLSLCRWCCNCCHNKGFAVAVVLACMCILESTAVPFSEVRTDEVGSIDSPVGEHQQPGGESMHPPELFRFKRQSHLSLCRWCCNCCHNKGCGFCCKF
    

Molecular Weight17903.64 Da

Isoelectric Point (pI)6.63

Net Charge (pH 7.0)-1.02

Net Charge (pH 7.4) -1.87

Charge Density (pH 7.0) -0.0063

GRAVY Index0.05

Hydrophobic Moment 0.49

Boman Index0.06

Instability Index83.43

Aliphatic Index 69.69

Aromaticity 0.0741

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 12000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7038.38

LogP -74.68

H-bond Donors 258.0

H-bond Acceptors 253.0

Rotatable Bonds 579.0

Heavy Atoms 1241.0

Ring Count 31.0

Amide Bonds 171.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0363861 VERIFIED: NO

Provenance & Taxonomy

OrganismCoregonus sp. `balchen` [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal