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MYP_001673
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Basic Information
Spheniscin-1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
38 amino acids
C194H309N69O43S6
Standard
Sequence
SFGLCRLRRGFCAHGRCRFPSIPIGRCSRFVQCCRRVW
Physicochemical Analysis
4488.36 Da
11.46
8.49
8.14
0.2234
-0.06
0.78
-0.20
50.22
58.95
0.1316
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1827.79
-18.76
76.0
59.0
143.0
312.0
9.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0096728 VERIFIED: YES
Provenance & Taxonomy
Aptenodytes patagonicus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
5-33; 12-27; 17-34
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Gram-positive bacteria; Gram-negative bacteria; fungi
qualitative antimicrobial assay
PaperSpheniscin-1 PMID14525994 Evidence URLhttps://www.uniprot.org/uniprotkb/P83429/entry
RECORD: Rec_0164945 VERIFIED: YES
Provenance & Taxonomy
Aptenodytes patagonicus [Animal]
Structure & Mods
disulfide-constrained peptide with linear backbone [Linear]
canonical L-amino-acid peptide [L]
5-33; 12-27; 17-34
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Gram-positive bacteria; Gram-negative bacteria; fungi
qualitative antimicrobial assay
PMID14525994
RECORD: Rec_0240872 VERIFIED: YES
Provenance & Taxonomy
Aptenodytes patagonicus [Animal]
Beta-defensin; Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
5-33; 12-27; 17-34
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Gram-positive bacteria; Gram-negative bacteria; fungi
qualitative antimicrobial assay
PMID14525994 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14525994/
RECORD: Rec_0283553 VERIFIED: YES
Provenance & Taxonomy
Aptenodytes patagonicus [Animal]
Defensin
Structure & Mods
disulfide-constrained peptide with linear backbone [Linear]
canonical L-amino-acid peptide [L]
None
None
5-33; 12-27; 17-34
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Gram-positive bacteria; Gram-negative bacteria; fungi
qualitative antimicrobial assay
PaperPubMed PMID: 14525994 PMID14525994 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14525994/
RECORD: Rec_0345848 VERIFIED: YES
Provenance & Taxonomy
Aptenodytes patagonicus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
5-33; 12-27; 17-34
Bio-Activity Profile
Antimicrobial Antifungal
Gram-positive bacteria; Gram-negative bacteria; fungi
qualitative antimicrobial assay
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123;14525994 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/