Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length488 amino acids

Chemical FormulaC2434H3856N638O679S21

DescriptionStandard

        MARGPCNAPRWASLLVLVVVGTAVAAAINPGVVVRISQKGLDYATQQGTAALQKELERIKIPDYSGSFKIKLLGKGHYSFYSMDIREFQLPSAQIRMVPNVGLKFSISNANIKISGKWKARKSFLKTSGGFDLSIGGTSISADLMLGSNLTSGKPTVTCASCSSHISSVHVHISNSKVGWLIQLFHKKIESALRNKLNSQVCQKLTSSVSSELQPYFQTLPVMTKIDAVAGIDYGLVAPPTITAETLDAQMKGEFYRLNHHNPPPFAPPVMEFPAAHDRMVYLGLSDYFFNTAGLVYQEAGVLKMTLTDDMIPKESRFRLTTKFFGSFLPEVAKMFPNMKMQIHISASVPPQLSVQPTGLSFFPALDIQAFAVLANSSLASLFLIGMSTHGSLEVSARSDRLVGELNVDRLLLELKHSTIGPFPVELLQDIMNYIVPTLVLPRVNVVSITERLQKGFPLPMPARVQFYNMVLQPHQNFLLFGADVVYK
    

Molecular Weight53593.88 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)13.53

Net Charge (pH 7.4) 12.55

Charge Density (pH 7.0) 0.0277

GRAVY Index0.13

Hydrophobic Moment 0.70

Boman Index0.14

Instability Index39.11

Aliphatic Index 97.48

Aromaticity 0.0881

Extinction Coeff. Reduced 35870.00

Extinction Coeff. Oxidized 36120.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409991 VERIFIED: NO

Provenance & Taxonomy

OrganismSapajus apella (Brown-capped capuchin) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria