Peptide Database

Peptide NameT-152

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC176H302N48O55S2

DescriptionStandard

        NIKENKCNGTDAKVKLIKQELDKYKNAVTELQLLM
    

Molecular Weight4034.70 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)1.75

Net Charge (pH 7.4) 1.52

Charge Density (pH 7.0) 0.0501

GRAVY Index-0.70

Hydrophobic Moment 0.58

Boman Index-0.18

Instability Index34.01

Aliphatic Index 100.29

Aromaticity 0.0286

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1740.59

LogP -15.94

H-bond Donors 58.0

H-bond Acceptors 59.0

Rotatable Bonds 148.0

Heavy Atoms 281.0

Ring Count 1.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0361309 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman orthopneumovirus [Virus]

FamilyVirus-derived peptide

Tax ID11250;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Fusion inhibitor

TargetRespiratory syncytial virus (Fusion); Vero

MethodImmunoprecipitation

PaperMethods for the inhibition of respiratory syncytial virus transmission | Dani Paul Bolognesi, Thomas James Matthews, Carl T. Wild, Shawn O'Lin Barney,Dennis Michael Lambert, Stephen Robert Petteway | Trimeris, Inc., Durham NC | Patent:US6440656 Evidence URLhttps://patents.google.com/patent/US6440656/en PatentUS6440656

RECORD: Rec_0415781 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral