Peptide Database

Peptide Namedefensin AFP precursor

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC357H559N105O108S10

DescriptionStandard

        MDKKSLAGLCFLFLVLFVAQEIAVSEAARCENLADTYRGPCFTTGSCDDHCKNKEHLVSGRCRDDFRCWCTRNC
    

Molecular Weight8370.55 Da

Isoelectric Point (pI)6.68

Net Charge (pH 7.0)-0.40

Net Charge (pH 7.4) -0.87

Charge Density (pH 7.0) -0.0054

GRAVY Index-0.17

Hydrophobic Moment 0.47

Boman Index-0.07

Instability Index24.80

Aliphatic Index 65.95

Aromaticity 0.0946

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3454.89

LogP -37.34

H-bond Donors 131.0

H-bond Acceptors 120.0

Rotatable Bonds 277.0

Heavy Atoms 580.0

Ring Count 11.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0213273 VERIFIED: YES

Provenance & Taxonomy

OrganismCicer arietinum [Plant]

FamilyDefensin

Tax ID3827

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal