Peptide Database

Peptide NameBovine neutrophil beta-defensin 12

Function Ontology

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Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC168H289N59O44S6

DescriptionStandard

        NPLSCRLNRGICVPIRCPGNLRQIGTCFRPSVKCCR
    

Molecular Weight4031.85 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)6.70

Net Charge (pH 7.4) 6.41

Charge Density (pH 7.0) 0.1861

GRAVY Index-0.10

Hydrophobic Moment 0.75

Boman Index-0.17

Instability Index37.75

Aliphatic Index 81.11

Aromaticity 0.0278

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1677.13

LogP -20.34

H-bond Donors 65.0

H-bond Acceptors 57.0

Rotatable Bonds 129.0

Heavy Atoms 277.0

Ring Count 5.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0208738 VERIFIED: YES

Provenance & Taxonomy

OrganismBos grunniens [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)