Peptide Database

Peptide NameSLAY-screened peptide P3190

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC101H155N35O27

DescriptionStandard

        PLSHTLPGHQRRASTNPWVH
    

Molecular Weight2291.53 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)2.22

Net Charge (pH 7.4) 2.01

Charge Density (pH 7.0) 0.1110

GRAVY Index-1.05

Hydrophobic Moment 0.37

Boman Index-0.14

Instability Index29.36

Aliphatic Index 58.50

Aromaticity 0.0500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 977.38

LogP -11.52

H-bond Donors 35.0

H-bond Acceptors 32.0

Rotatable Bonds 67.0

Heavy Atoms 163.0

Ring Count 8.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143840 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/