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MYP_001620
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Anti-Pneumovirus ▸ Anti-RSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Standard
35 amino acids
C190H291N45O62S
Standard
Sequence
VDFLEENITALLEEAQIQQEKNMYELQKLNSWDVF
Physicochemical Analysis
4229.67 Da
4.05
-6.25
-6.48
-0.1786
-0.47
0.41
0.01
56.95
100.29
0.1143
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1781.27
-13.08
57.0
57.0
146.0
298.0
5.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0028421 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Evidence URLhttps://patents.google.com/patent/US6228983B1/en PatentUS 6228983 B1
RECORD: Rec_0040122 VERIFIED: YES
Provenance & Taxonomy
Simian immunodeficiency virus [Virus]
Virus-derived peptide
11723;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor Fusion inhibitor
Simian immunodeficiency virus (gp160)
Cell-fusion assay
PaperFusion proteins comprising DP-178 and other viral fusion inhibitor peptides useful for treating aids | Dani Paul Bolognesi, Thomas James Matthews, Carl T. Wild, Durham, Shawn O'Lin Barney, Dennis Michael Lambert, Stephen Robert Petteway, Alphonse J. Langlois | Duke University, Durham, NC (US) | Patent:US7122190 Evidence URLhttps://patents.google.com/patent/US7122190/en PatentUS7122190
RECORD: Rec_0130847 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Fusion inhibitor
CEM
Qualitative inhibition
PaperMethods and compositions for treatment of HIV-1 infection using antiviral compounds in simultaneous or sequential combinations PatentUS6861059
RECORD: Rec_0143900 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0263360 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Respiratory syncytial virus fusion-inhibitory peptide
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-RSV Fusion inhibitor
Simian immunodeficiency virus
PaperHuman respiratory syncytial virus peptides with antifusogenic and antiviral activities Evidence URLhttps://patents.google.com/patent/US6228983B1/en PatentUS 6228983 B1
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