Peptide Database

Peptide NameCloacin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length561 amino acids

Chemical FormulaC2580H4120N766O823S8

DescriptionStandard

        MSGGDGRGPGNSGLGHNGGQASGNVNGTSGKGGPSSGGGTDPNSGPGWGTTHTPNGDIHNYNPGEFGNGGSKPGGNGGNSGNHSGSSGGGQSSATAMAFGLPALATPGAEGLALSFSGDALSSAVADVLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSKIMTSLPADTVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKPTKRPGVFSVSIPGLPALQVSVPKGVPAAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIRFPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKREYDKAKAELDAEDKNITTLNGRITSTEKAIPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQVRYLDKDIQNQNAKLKAAQASLNAMNDALSRDKAALSGAMESRKQKEKKAKEAENKLNEEKKKPRKGTKDYGHDYFPDPKTEDIKGLGELKEGKPKTPKQGGGGKRARWYGDKKRKIYEWDSQHGELEGYRASDGEHLGAFDPKTGKQVKGPDPKRNIKKYL
    

Molecular Weight59293.47 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)14.44

Net Charge (pH 7.4) 13.53

Charge Density (pH 7.0) 0.0257

GRAVY Index-0.83

Hydrophobic Moment 0.64

Boman Index-0.12

Instability Index35.31

Aliphatic Index 59.20

Aromaticity 0.0535

Extinction Coeff. Reduced 52370.00

Extinction Coeff. Oxidized 52370.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0098479 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyColicin/Bacteriocin

Tax ID573

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence

RECORD: Rec_0162131 VERIFIED: NO

Provenance & Taxonomy

OrganismCitrobacter freundii [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease

TargetEscherichia coli