Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2294H3639N623O652S10

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGITILEKELSQLKLSDISGDSRVGRVGKVHYELSRLRLRDFHLPYSRITPISNVGLQVSISNAFAELDGDWRVKFLFVRDHGSFNLKVENVYIKISLRLGSDASGKPTISTSECSARISKVRVLFSGRLGWLYNLFHRAIESRLRKILEEKVCVIVDKSVQNELQKYVQTLPVTARIDNKTGIDYSLVAPPRATAQSLDADLKGEFYSLAHRSTVPFSPLPLAFPSDHDRMVYFGASSYFFNTAAIAYHEAGALVFEITENMIPKDAGFSLDTSIFSAFIPQLEEMYPNMPMKFRLSTPTAPFLTIGPGGISLKPTVDAQAYAILPDGSLAPLFLLSLVRNVSAVINVRSGHIVGSLDVGRIRLSLKDSAVGTFEVRMMQSLMNILTSSTLLPRLNARLDEGFPLPLLDRIQLSNTLVRFHQNFLLLGADVHFQPR
    

Molecular Weight50698.86 Da

Isoelectric Point (pI)9.25

Net Charge (pH 7.0)7.38

Net Charge (pH 7.4) 6.51

Charge Density (pH 7.0) 0.0162

GRAVY Index0.04

Hydrophobic Moment 0.70

Boman Index0.08

Instability Index32.60

Aliphatic Index 102.83

Aromaticity 0.0899

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30495.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0138891 VERIFIED: NO

Provenance & Taxonomy

OrganismRhipidura dahli [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria