Peptide Database

Peptide NameManserin

Function Ontology

Cardiovascular

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC182H296N50O72S

DescriptionStandard

        VPSPGSSEDDLQEEEQLEQAIKEHLGQGSSQEMEKLAKVS
    

Molecular Weight4368.65 Da

Isoelectric Point (pI)4.22

Net Charge (pH 7.0)-7.16

Net Charge (pH 7.4) -7.44

Charge Density (pH 7.0) -0.1789

GRAVY Index-1.07

Hydrophobic Moment 0.52

Boman Index-0.17

Instability Index89.90

Aliphatic Index 68.25

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1997.21

LogP -24.95

H-bond Donors 64.0

H-bond Acceptors 67.0

Rotatable Bonds 155.0

Heavy Atoms 305.0

Ring Count 3.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326067 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyManserin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other Mods6:Phosphoserine; 29:Phosphoserine; 30:Phosphoserine

Bio-Activity Profile

Function

Cardiovascular Growth regulation Development regulation Immunomodulatory ACE inhibitory

Half-LifeMammalian: 100 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0393180 VERIFIED: NO