Peptide Database

Peptide NameUnnamed

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC34H51N7O7S

DescriptionStandard

        VVCVPW
    

Molecular Weight701.88 Da

Isoelectric Point (pI)5.49

Net Charge (pH 7.0)-0.28

Net Charge (pH 7.4) -0.50

Charge Density (pH 7.0) -0.0460

GRAVY Index2.10

Hydrophobic Moment 0.15

Boman Index0.74

Instability Index23.07

Aliphatic Index 145.00

Aromaticity 0.1667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 215.82

LogP 0.95

H-bond Donors 8.0

H-bond Acceptors 8.0

Rotatable Bonds 16.0

Heavy Atoms 49.0

Ring Count 3.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0288934 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetACE

RECORD: Rec_0298048 VERIFIED: YES

Provenance & Taxonomy

OrganismMactra veneriformis [Animal]

FamilyAngiotensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-converting enzyme

Activity4.1 μM

MethodIC50

RECORD: Rec_0324558 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory

TargetAngiotensin-converting enzyme (ACE)

Activity4.07

PaperLiu R., Zhu Y., Chen J., Wu H., Shi L., Wang X., Wang L.. Characterization of ACE inhibitory peptides from Mactra veneriformis hydrolysate by nano-liquid chromatography electrospray ionization mass spectrometry (Nano-LC-ESI-MS) and molecular docking. Mar. Drugs, 12, 3917-3928, 2014. Evidence URLhttps://pmc.ncbi.nlm.nih.gov/articles/PMC4113806/