Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length229 amino acids

Chemical FormulaC1153H1774N264O350S8

DescriptionStandard

        QIDDLAEVDYSLSSLPAVFRPFIDLDLKGVVFPAGNYTDSPYEAACFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNVIIAEETCSYYNINTEIFGSIIPEVAKYSVTPYPVMLKLMSTEIPVISLQQDSFTLEVQGSMEVLAVLPDSTTQSLLTLSIAANTSISLNIFNKKLMGSLCLNRIQFSLAHSNVGSFEVLPLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight25190.50 Da

Isoelectric Point (pI)4.17

Net Charge (pH 7.0)-14.15

Net Charge (pH 7.4) -14.51

Charge Density (pH 7.0) -0.0618

GRAVY Index0.32

Hydrophobic Moment 0.60

Boman Index0.24

Instability Index49.48

Aliphatic Index 103.06

Aromaticity 0.1179

Extinction Coeff. Reduced 17880.00

Extinction Coeff. Oxidized 18005.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0175856 VERIFIED: NO

Provenance & Taxonomy

OrganismIlladopsis cleaveri [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria