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MYP_001469
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Basic Information
Sarcotoxin-1D
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
40 amino acids
C189H312N62O56
Standard
Sequence
GWIRDFGKRIERVGQHTRDATIQTIAVAQQAANVAATLKG
Physicochemical Analysis
4348.88 Da
10.83
2.85
2.59
0.0713
-0.31
0.97
-0.06
24.52
88.00
0.0500
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1950.60
-22.31
69.0
60.0
147.0
307.0
4.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0109265 VERIFIED: YES
Provenance & Taxonomy
Sarcophaga peregrina [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Pseudomonas lachrymans
PaperPubMed PMID: 3182836 PMID3182836 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3182836/
RECORD: Rec_0117252 VERIFIED: YES
Provenance & Taxonomy
Sarcophaga peregrina [Animal]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0120030 VERIFIED: YES
Provenance & Taxonomy
Flesh fly [Animal]; Insecta [Animal]
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID3888997 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3888997/
RECORD: Rec_0129177 VERIFIED: YES
Provenance & Taxonomy
Sarcophaga peregrina [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Proteus vulgaris
PMID3182836 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3182836/
RECORD: Rec_0137936 VERIFIED: YES
Provenance & Taxonomy
Sarcophaga peregrina [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Corynebacterium bouis
PaperPubMed PMID: 3182836 PMID3182836 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3182836/
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