Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC169H280N50O55S2

DescriptionStandard

        KCNTATCVTQRLANFLVRSSNNLGAILLPTDVGSNTY
    

Molecular Weight3956.46 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0470

GRAVY Index0.06

Hydrophobic Moment 0.67

Boman Index0.05

Instability Index17.61

Aliphatic Index 94.86

Aromaticity 0.0541

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1729.86

LogP -23.37

H-bond Donors 62.0

H-bond Acceptors 59.0

Rotatable Bonds 128.0

Heavy Atoms 276.0

Ring Count 3.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0143973 VERIFIED: YES

Provenance & Taxonomy

OrganismMustela putorius [Animal]

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)