Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC478H773N119O135S8

DescriptionStandard

        MKLFLVLIILLFEVPTDGAGLRKCFNNITGYCRKKCKIGEIYEVGCLSGKLCCVNEEESKIYLKAHKPREPDGEVSDGKMDYVILPTITLFTIQ
    

Molecular Weight10603.49 Da

Isoelectric Point (pI)7.55

Net Charge (pH 7.0)0.54

Net Charge (pH 7.4) 0.15

Charge Density (pH 7.0) 0.0058

GRAVY Index0.09

Hydrophobic Moment 0.56

Boman Index0.09

Instability Index29.48

Aliphatic Index 103.62

Aromaticity 0.0851

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4071.76

LogP -29.06

H-bond Donors 145.0

H-bond Acceptors 145.0

Rotatable Bonds 360.0

Heavy Atoms 740.0

Ring Count 13.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0369718 VERIFIED: NO

Provenance & Taxonomy

OrganismPropithecus coquereli [Bacterium]

FamilyDefensin

Tax ID379532

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence