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MYP_001403
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Basic Information
Tigerinin 3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
12 amino acids
C66H103N15O15S2
Standard
Sequence
RVCYAIPLPICY
Physicochemical Analysis
1410.75 Da
8.05
0.74
0.50
0.0615
1.12
0.37
0.36
42.55
130.00
0.1667
2980.00
3105.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
468.20
-0.42
18.0
18.0
38.0
98.0
4.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0281061 VERIFIED: NO
Provenance & Taxonomy
Rana tigerina [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0281666 VERIFIED: YES
Provenance & Taxonomy
Indian bullfrog [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-11
Bio-Activity Profile
Antimicrobial
Bacillus subtilis; Staphylococcus aureus ATCC 8530; Escherichia coli W160.37; Pseudomonas putida NCIM 2102; Micrococcus luteus MT 166; Saccharomyces cerevisiae ATCC 8530
30;30;40;40;30;80 μg/mL
MIC
PMID11031261 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11031261/
RECORD: Rec_0293720 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0296914 VERIFIED: YES
Provenance & Taxonomy
Hoplobatrachus tigerinus [Animal]
Tigerin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
3-11
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
28.0 μM
MIC
PaperK.P. Sai et al. / The Journal of Biological Chemistry 276 (2001) 2701-2707. Tigerinins: Novel Antimicrobial Peptides from the Indian Frog Rana tigerina PMID11031261 Evidence URLhttps://www.uniprot.org/uniprotkb/P82653/entry
RECORD: Rec_0329159 VERIFIED: YES
Provenance & Taxonomy
Rana tigerina [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-11
It contains one disulfide bond
Bio-Activity Profile
Antimicrobial Antifungal
Bacillus subtilis
30 μg/mL
MIC
PaperTigerinins: novel antimicrobial peptides from the Indian frog Rana tigerina. PMID11031261
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