Peptide Database

Peptide NameHainantoxin V

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC166H262N52O50S6

DescriptionStandard

        ECLGFGKGCNPSNDQCCKSANLVCSRKHRWCKYEI
    

Molecular Weight3978.56 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)2.86

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.0818

GRAVY Index-0.68

Hydrophobic Moment 0.39

Boman Index-0.19

Instability Index50.66

Aliphatic Index 44.57

Aromaticity 0.0857

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1681.46

LogP -20.33

H-bond Donors 64.0

H-bond Acceptors 60.0

Rotatable Bonds 133.0

Heavy Atoms 274.0

Ring Count 6.0

Amide Bonds 38.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0134717 VERIFIED: NO

Provenance & Taxonomy

OrganismSelenocosmia hainana,Haplopelma hainanum,Ornithoctonus hainana [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-17; 9-24; 16-31

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0318437 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 31.4%, T 37.1%, C 31.4% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic