Peptide Database

Peptide NameT-1-conotoxin Ca5.2

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC59H80N14O17S4

DescriptionStandard

        CCPESPPCCHYF
    

Molecular Weight1385.61 Da

Isoelectric Point (pI)5.24

Net Charge (pH 7.0)-1.19

Net Charge (pH 7.4) -1.51

Charge Density (pH 7.0) -0.0992

GRAVY Index-0.07

Hydrophobic Moment 0.14

Boman Index0.14

Instability Index165.92

Aliphatic Index 0.00

Aromaticity 0.1667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 463.49

LogP -4.02

H-bond Donors 18.0

H-bond Acceptors 21.0

Rotatable Bonds 34.0

Heavy Atoms 94.0

Ring Count 6.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0253246 VERIFIED: NO

Provenance & Taxonomy

OrganismConus caracteristicus [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide1-8; 2-9

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0363974 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic