Peptide Database

Peptide NameNeutrophil defensin 4 (Defensin, alpha 4; primates, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC161H266N50O46S6

DescriptionStandard

        VCSCRLVFCRRTELRVGNCLIGGVSFTYCCTRVD
    

Molecular Weight3830.53 Da

Isoelectric Point (pI)8.70

Net Charge (pH 7.0)2.68

Net Charge (pH 7.4) 2.38

Charge Density (pH 7.0) 0.0788

GRAVY Index0.54

Hydrophobic Moment 0.59

Boman Index0.01

Instability Index56.09

Aliphatic Index 88.53

Aromaticity 0.0882

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1572.19

LogP -17.57

H-bond Donors 65.0

H-bond Acceptors 55.0

Rotatable Bonds 124.0

Heavy Atoms 263.0

Ring Count 3.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0061253 VERIFIED: YES

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Tax ID9598

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

RECORD: Rec_0297670 VERIFIED: NO