Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2311H3611N619O633S12

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGIAVLEKELAHLKLPDISGDFRLRHVAKVHYEISRLDLRSFHLPYSRISLVPNVGLQVSISNAFAEMDGNWRVKMYFIRDHGSFDLKVENVYIKISLKLGSDASGKPTIDTSDCSTRISKVWVHFSGKFGWLYNLFRDAIESRFRKILESKVCENVVSSVRSELQPYARTLPVTARIDAMAGIDYSLVAPPTATAQSLDVGLKGEFFSLARRSAVPFPPLALAFPPDHDRMVYFGASSYFFNTAGFAYHAAGALVFEIADSTIPKGVDFHLNTTTFSAFIPQLEKMYPDMPMKLRLSTPSAPFLNVGPGGLSLRPVVDMQAYAILPNASLAPLFLLGVVSNVSAVIDVKSGHIVGSLKVGRIKLSLKHSDVGTFQVRMLQSIMNIFASNILVPRFNARLDQGFPLPLPDRIQLSNILVRFHQNFLLLGADVHYQPR
    

Molecular Weight50578.94 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)10.63

Net Charge (pH 7.4) 9.61

Charge Density (pH 7.0) 0.0233

GRAVY Index0.11

Hydrophobic Moment 0.70

Boman Index0.12

Instability Index38.31

Aliphatic Index 99.63

Aromaticity 0.1031

Extinction Coeff. Reduced 37360.00

Extinction Coeff. Oxidized 37485.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0421270 VERIFIED: NO

Provenance & Taxonomy

OrganismOceanodroma tethys (Wedge-rumped storm-petrel) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria